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Injections: Injections bypass the digestive system, leading to faster absorption and potentially more noticeable effects in a shorter time frame

Larger randomized placebo-controlled trials including a variety of patient populations (ie, those with metabolic syndrome versus those without) are needed to confirm efficacy of GLP-1RAs according to patient type

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Compounded formulations prepared by licensed pharmacies registered with FDA as facilities may differ in bioavailability, consistency, inactive ingredients, or other factors potentially affecting clinical outcomes