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Biosci Microbiota Food Health

SS: Resources, Validation, Writing review and editing, Data curation, Investigation

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Besides xCT/GPX4 inhibition (by Erastin/Sulfasalazine/RSL3), 379,380,381 FSP1 inhibitors (iFSP1, Liproxstatin-1) and DHODH blockers (TPP-brequinar/B2, Leflunomide) disrupt organelle membranes and mitochondrial antioxidants, respectively

966, 245252.10.1016/S0006-8993(02)04174-4 228 SakamotoT.CansevM.WurtmanR

It is proposed that few side effects occur, since it seems that hydrogen reacts with strong oxidants and its levels does not seem to interfere with cell signaling processes involving reactive oxygen species [2]