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Government agencies, medical boards, and public health organizations are warning patients and healthcare providers about the risks of compounded semaglutide." The safety risks from continued mass compounding of GLP-1s are heightened because compounded GLP-1s rely on a supply of active pharmaceutical ingredients (API) from dangerous and illegal foreign sources. 9 Center for Medicine in the Public Interest there can be errors in compounding or contamination of the product because compounding pharmacies are not held to the same standards of larger drug manufacturers. 10 National Capital Poison Center Download a summary guide of this page