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L-theanine ameliorated 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced erythema, increased vascular permeability, epidermal and dermal hyperplasia, and neutrophil infiltration via decreasing platelet endothelial cell adhesion molecule (PECAM)-1 expression and the production of pro-inflammatory cytokines including IL-1, tumor necrosis factor (TNF)- and cyclooxygenase (COX)-2 [34]

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The influence of various factors leads to the difference in the composition of calculi in patients with urinary calculi, among which the proportion of calcium oxalate stones and the mixed stone of calcium oxalate and calcium phosphate stones accounts for approximately 70%