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Description
The copper peptide evidence includes a 2012 review by Pickart et al

Role of Glutathione, Glutathione Transferase, and Glutaredoxin in Regulation of Redox-Dependent Processes
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Collectively called ROS (reactive oxygen species) they can create havoc in the cell and are implicated in many processes of aging

and by accompanying liver injury

Sleep deprivation induces upregulation of the main Cl-accumulating transporter, NKCC1/SLC12A2, resulting in increased neuronal Cl accumulationa reversible process modified by the NKCC1 inhibitor bumetanide 107
J Sci Food Agric 2000
