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Sex differences in autism spectrum disorder: diagnostic, neurobiological, and behavioral features

In: Adashi E.Y., Mancuso S., editors

We have produced a large-scale computational biology analysis of the SNO-proteome in the cortex of Shank3 mutant mice (a popular model of ASD [171, 282, 283]) and found that among the NO-related molecular alterations, the most prominent change was the activation of the mTOR signaling pathway [171, 176]

It plays a crucial role in lipid metabolism by transporting long-chain fatty acids into the mitochondria, where they are oxidised for energy production

Primary pain in ALS includes neuropathic pain and pain due to spasticity or cramps, whereas secondary pain is mainly nociceptive and may appear as muscle weakness and atrophy progress [83]

Antioxidants 9, 1040
