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On this basis, it was suggested that inhibitors that block the association of JNKs within the mitochondria might be useful neuroprotective agents for the treatment of PD [27], and probably dysfunction in the projections of dopaminergic neurons of the nigrostriatal DA pathway from the substantia nigra to the dorsal striatum would slowly lead to PD [29]

Inhibition or down-regulation of ODC1 breaks this vicious cycle and promotes astrocytic detoxification of -amyloid

Allen, 2021), and is been considered a keystone pathogen that can reshape the surrounding microbiota (Hajishengallis et al., 2012)

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