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It has been proposed that the circulating peptide could access the brain via the ARC and exert its anorectic actions through indirect activation of pro-opiomelanocortin (POMC) neurons in the hypothalamus and through the blocking of fasting ghrelin levels

298 Additionally, promoting mitophagy also helps mitigate the inflammatory response in aging

doi: 10.3390/antiox12030607 258

It seems to enhance the effects of those treatments

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Hepatic Chylomicron Remnant Uptake Chylomicron remnants, containing primarily cholesteryl esters, apoE, and apoB-48, are then delivered to, and taken up by, the liver
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