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confirmed that TFAP2C regulated GPx1 expression by directly binding to the GPx1 promoter, which contains an AP-2 regulatory region, and the methylation of the CpG island in the GPx1 promoter region prevented the binding of TFAP2C by encompassing the AP-2 regulatory region [81]

Although the field of ferroptosis remains in its infancy, several promising targets and treatment approaches have already been identified

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Transcriptional factor icer promotes glutaminolysis and the generation of Th17 cells

In parallel, post-synthetic remodeling of PC represents a complementary target space

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