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We hypothesized that GSH and GABA concentrations would be significantly lower in autism compared to TDC in all four brain regions

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The main mechanism responsible for Graves hyperthyroidism is the activation of the thyroid-stimulating hormone receptor (TSHR) by autoantibodies that act as agonists, causing thyrocyte proliferation and hyperfunction

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Thus, while both possible strategies can be used depending on end structure, the extreme favoring of one path over the other argues that there is little flexibility in the choice of path for a given end structure