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Tirapazamine suppress osteosarcoma cells in part through slc7a11 mediated ferroptosis

Parker, et al., Proc

Bacteroides thetaiotaomicron and Lactobacillus johnsonii generate fatty acids, particularly oleic acid and palmitic acid, regulate inflammatory immune responses, and eliminate Candida glabrata in the DSS-induced colitis mouse model ( Current antifungal drugs Currently, the first-line clinical antifungal drugs include polyenes (e.g., amphotericin B), azoles (e.g., fluconazole) and echinocandins (e.g., caspofungin) (Wiederhold, 2017
Additionally, ferroptosis inducer Erastin exacerbated Lipid ROS levels (Fig
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