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Scoring systems: Sigstad scoring system

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Neves JS, Vasques-Nvoa F, BorgesCanha M, Leite AR, Sharma A, Carvalho D, et al

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The shorter trial duration of SUSTAIN 6 and PIONEER 6 compared with the 3.5-year trial duration of LEADER might also explain the observed discrepancy in treatment effect across baseline eGFR subgroups [2], because eGFR decline is a continuous process and a follow-up of 2 years is recommended to reliably predict a treatment effect based on changes in eGFR slope [26]