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Analysis of acylcarnitines as their N-demethylated ester derivatives by gas chromatography-chemical ionization mass spectrometry

V., Saudubray, J

In order to discuss the findings of the present study in reference to previous work, it is useful to first consider the known metabolic functions of carnitine and its acyl variations

Thus ALCAR provides both carnitine for the transport of fatty acids across mitochondrial membranes, and acetyl-CoA that can be incorporated into lipids [114], oxidized in the TCA cycle for energy production and incorporated into neurotransmitters [1, 57]

Using the power of the zebrafish model, researchers are able to establish novel insights into pathomechanisms of CM and provide the necessary groundwork for future therapy development [8]

[DOI] [PubMed] [Google Scholar] 61.Karsan N., Prabhakar P., Goadsby P.J