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Upon exceeding 150 CAG repeats, MSNs undergo progressive loss of neuronal characteristics while concurrently upregulating senescence-related and pro-apoptotic gene programs, culminating in neuronal degeneration

11 An important point is that this innate stability (as mentioned, resistant to degradation in human gastric juice more than 24 hours) provides the advantage of the administration using various routes of applications

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Kotopoulou S, Zampelas A, Magriplis E

doi: 10.1111/j.1365-3040.2004.01217.x 175 RonzanM.PiacentiniD.FattoriniL.Della RovereF.EicheE.RiemannM.et al

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