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Recent research supports a prion-like propagation model, where pathogenic -synuclein spreads trans-neuronally via exosomes and synaptic transmission, initiating a chain reaction of misfolding across interconnected brain regions

One-way analysis of variance (ANOVA) and Duncans multiple range test were used for variance analysis and multiple comparisons ( = 0.05)

Targeting oxidative stress with compounds like vitamin E, coenzyme Q10, or polyphenols may help mitigate oxysterol-induced damage

GHK-Cus mechanism depends on cumulative tissue signaling rather than peak concentration

Texh-prog-like cells that are clonally related to Texh cells in the tumor migrate from the TDLNs to the tumor, sustain the anti-tumor T cell response, and eventually undergo differentiation to terminal exhaustion 58, 64, 66, 263, 264