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Different studies demonstrated that linoleic acid has several benefits for hair metabolism: it may help reduce inflammation and regulate sebum production in the scalp that can cause hair loss

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doi : 10,1016/j.lfs.2014,05,022

The ability of Aifm1 inhibition and Parga overexpression to phenocopy the effects of Nampt and Parp inhibition in the Spint1a-deficient model further confirmed that parthanatos induced by Parp1 overactivation, rather than by depletion of ATP and NAD + keratinocyte stores, mediated skin inflammation (Fig 8)