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doi: 10.1038/s41467-020-15068-4 102 SpadoniIZagatoEBertocchiAPaolinelliRHotEDi SabatinoAet al
Update 27 , 2747 (2021)

80 Senescent RPE cells secrete SASP factors like interleukins (IL-6, IL-8), vascular endothelial growth factor (VEGF), and matrix metalloproteinases (MMPs), which promote inflammation, neovascularization, and extracellular matrix remodeling

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Millions of people have a B12 deficiency

Cell (2022) 185:240121
