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It builds over weeks instead of arriving all at once

Tumour-associated neutrophils (TANs) can promote a hypoxic microenvironment and immunosuppression [226]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 184.Schwarz L., Kindermann W

Considering that the ROS-ATM-p53 signaling pathway contributes to the induction of Lpin1 and G6PD greatly influences ROS levels, it is reasonable to hypothesize that G6PD may regulate p53 function
