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Ademola, J., Ajgaonkar, A., Debnath, T., et al
doi: 10.1074/jbc.M113.529966
Prinz et al
Glutathione biosynthesis: -glutamylcysteine synthetase from rat kidney
Despite the emergence of several human cohort studies in the last 5 years, few are truly integrative
However, the safety and feasibility of this approach has not been fully validated in humans, and a number of potential issues need to be addressed, such as the precision of gene editing, nonspecific side effects, effective vectors and delivery systems, and ethical and legal regulations
