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Rats were group-housed, three per cage, under controlled environmental conditions: a 12-h light/dark cycle (lights on at 7:30 AM and off at 7:30 PM), constant temperature (25 C), and ad libitum access to standard rodent chow (Rodent Diet CE-2, CLEA Japan, Tokyo, Japan) and tap water

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The DI was calculated as follows: ([novel object exploration time/total exploration time] [familiar object exploration time/total exploration time]) 100

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