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Third, the APP/PS1 transgenic mouse model of Alzheimers disease used in Sun 2021 to test Dihexa in an amyloid-pathology model, with Morris water maze, neuroinflammatory cytokines, and PI3K/AKT pathway activation as primary readouts

Abouesh A, Stone C, Hobbs WR

Besides their protein and lipid profiles, MEVs contain several nucleic acids, including mRNAs, microRNAs, and double-stranded DNAs

doi: 10.1155/2019/8197580

Notably, serotonin synthesis decreased in dorsal thalamus, hippocampus, lateral geniculate body, and hypothalamus

Loss of At4 function impacts phosphate distribution between the roots and the shoots during phosphate starvation
