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One more sodium glucose co-transporter 2 inhibitor (SGLT2i) trial showing benefit

These medications target fundamentally different hormonal systemsone endocrine, one metabolic-signalingwhich suggests additive rather than overlapping effects

Mahendran, A

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Clin Transl Med 6(1):19

Original studies were prioritized when they directly examined how amino acid metabolic pathways regulate macrophage polarization, inflammatory function, or disease-associated immune phenotypes in in vitro systems, animal models, or human samples