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11 Abad, C., Amengual, M

Subsequently, Nrf2 accumulates and translocates to the nucleus, where it binds to the Antioxidant Response Element (ARE), initiating the transcription of a battery of cytoprotective genes responsible for counteracting inflammation and oxidative stress

doi: 10.1136/bcr-2019-231888

Interestingly, de novo PD following VED use has been described in two case reports, and is thought to be secondary to trauma associated with VED use

589(Pt 4):963-73

Provides flavour
