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Description
The ability of cells to respond to this threat by the up regulation of GSH biosynthesis provides an intricate balance of reducing to oxidizing equivalents, allowing the redox homeostasis in the cell to be maintained
Longevity 11 , 4501097
The research picture is nuanced
Nature 554 , 544548 (2018)
In mammals, PRDX14 preferentially detoxify H 2 O 2 , whereas PRDX5 shows higher reactivity toward alkyl hydroperoxides and peroxynitrite, and PRDX6 reduces both H 2 O 2 and LOOHs
[DOI] [PubMed] [Google Scholar] 406.Zhang Y
