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This may occur due to aging, certain diets, or medications such as Metformin, which is commonly used to treat diabetes

Behavioural analysis PPIacoustic startle response and PPI The test was performed using the SR-LAB Startle Response System apparatus (San Diego Instruments), as previously described (51, 52)

Another issue of concern that must be comprehensively explored in future trials is the association between tesofensine and increased frequency of agitation and mood changes