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Animal studies (e.g., on diet-induced obese mice) show reduced body weight and fat mass without muscle loss

It is a mitochondrial (energy) form of B12 that is usually great for people who have general tiredness/fatigue or they are easily fatigued with small amounts of exercise

Tanabe, S., et al

In principle, these distinct entry points could produce additive AMPK activation, but this dual activation has not been formally studied in humans and warrants physician oversight, particularly regarding blood glucose monitoring
