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Similarly, an 11-bp deletion mutation in the E1 subunit of the BCKDH complex that results in a change to the reading frame and subsequent E1 instability, also causes a decrease in enzymatic function in vitro (Nobukuni et al., 1991)

Muscle Recovery A double-blind, placebo, crossover study found that 2 g of L-carnitine had positive effects and significantly attenuated markers of purine metabolism, free radical formation, muscle tissue disruption, and muscle soreness after physical exertion

Combining L-carnitine with strength training may also help shed extra pounds by promoting fat burning

J Oral Microbiol

Manufacturers who stay abreast of these developments can create more targeted, science-backed formulations

Mapping and refactoring pathway control through metabolic and protein engineering: the hexosamine biosynthesis pathway