glutathione glu-cys-gly Chemical structure of the tripeptide (γ-Glu-Cys-Gly) Glutathione-driven redox decisions in cell

Anti-ferroptotic genes and lipid metabolism genes are highlighted

& Feman, S

The long non-coding RNA MALAT1 activates the NRF2 transcription factor, enhancing the expression of antioxidant genes such as HO1, NQO1, and GCLC, which helps protect cells from oxidative stress-induced damage [167]

In a linked fashion, our data from immunoblot analysis showed that canagliflozin induces AMPK in a concentration-dependent manner

S., & Choi, K

Deficiencies in the Nrf2 factor not only increase susceptibility to oxidative stress but also prevent melanocytes from maintaining proper redox balance, leading to sustained ROS production and greater melanocyte vulnerability 113