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Adding more methylated B vitamins can make things worse

Is glutathione deficiency common in people starting GLP-1 medications? No

Biocatal Agric Biotechnol 43:102417 [Google Scholar] Topal F, Topal M, Gocer H, Kaln P, Koyiit UM, Gulcin I, Alwasel SH (2016a) Antioxidant activity of taxifolin: an activity-structure relationship

Regular B12 injections can reduce feelings of stress or anxiety, increase mental clarity, and improve overall mood

Arabian Journal of Chemistry , 16 , 105000

It is possible that children with lower baseline glutathione levels may need a higher dose or a longer intervention to attain similar behavioral outcomes