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Nucleoside-analog reverse transcriptase inhibitors such as adefovir dipivoxil are well known for their mitochondrial toxicity and may be involved in HIV-associated neurodegeneration and other accelerated aging phenotypes ( Statements Data availability statement The original contributions presented in the study are included in the article/Supplementary Material, further inquiries can be directed to the corresponding authors

Varella-Garcia M, Murata-Collins J, Berger R, Andreeff M , Ai H, Richkind K, McGavran L, Paskulin G, Erickson P, Drabkin H

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Caf-au-lait macules (L81.3) differ by presenting in childhood and lacking sun-exposure correlation

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