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In addition, the accumulation of acylcarnitine in the pathological state of the liver leads to insulin resistance, which further aggravates the development of liver diseases and results in a vicious cycle [211]

Overall, most studies reported improvements in exercise capacity, muscle function, and mitochondrial metabolism, with no changes observed in creatine kinase (CK) levels or mutation burden

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doi: 10.2147/DDDT.S386974

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