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Methods A systematic review of the literature using the MEDLINE database (search dates 1/1/83-7/22/09) was conducted to identify peer-reviewed publications relevant to the diagnosis and treatment of IC/BPS

with sedentary behavior offering no benefit (278)Shreves AH, et al

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Mechanism-based treatments for human illnesses offer superior efficacy and improved tolerability

A structured assessment can determine eligibility for existing licensed treatments, referral to a specialist weight management service (in line with NICE CG189), or enrolment in a clinical trial