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Transient discolouration of tissue at the injection site is possible

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The CIs are surgically implanted to directly stimulate the auditory nerve by bypassing the outer and middle ear, and are indicated for severe and profound bilateral sensorineural/conductive hearing loss (Michels et al., 2019)

doi: 10.1016/j.jcis.2024.04.111 119

The first use of the idea of affinity chromatography may be considered as the isolation of -amylase by using an insoluble substrate, starch, in 1910 by Starkenstein [6,9]