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doi: 10.3389/fcell.2025.1598924 Received 24 March 2025 Accepted 07 July 2025 Published 18 July 2025 Volume 13 - 2025 Edited by Junqi Huang, Jinan University, China Reviewed by Anna Martina Battaglia, Magna Grcia University of Catanzaro, Italy Cadiele Oliana Reichert, University of So Paulo, Brazil Updates Copyright 2025 Fan, Xu, Gao, Zhang, Wang, Shan, Luo, Fei and Cai

BSO treatment causes a significant reduction of the total GSH in liver (70 %), which is attributable to the diminished levels of the reduced GSH (GSH, 71 %) in rats [12]

These features included abnormal accumulation of lipid peroxides and ROS (38)

The mice were injected with BPC157 three times per week, and the results were compared with a cancer cachexia control group

RSL3 alone did not reduce tumor volume or weight compared to the control

Over time, oxidative stress can contribute to the visible signs of ageing, persistent brain fog, and a general decline in physical resilience