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FIGURE 2 Causes of B12 deficiency and criteria for diagnosis The absorption and metabolic pathway for B12 is highly complex, and defects in any part of this process can lead to therapeutic B12 replacement

If PLC is activated, the plasma membrane component PIP2 is cleaved into DAG and IP3

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doi:10.1093/ibd/izae020.021

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G.JakesR.RutherfordD.CrowtherR
