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Earlier work demonstrated that BM cells from MM aspirates express CD38, CD203a, CD73, and CD26, with malignant plasma cells characterized by high CD38 expression and variable CD203a positivity, whereas CD73 is largely restricted to stromal and osteogenic cells (45)

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These symptoms arise due to the bodys reduced ability to produce healthy red blood cells, leading to decreased oxygen supply to tissues

doi:10.1159/000053183 Heffernan MA, Thorburn AW, Fam B, et al