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When present in saturated concentration, the drug can overcome excretion through the transmembrane pump, reducing the loss of the drug from the microbial cells

doi: 10.1152/japplphysiol.00833.2002

doi: 10.1016/j.cmet.2021.06.014 Summary Keywords chronic kidney disease, gut-brain-kidney axis, gut microbiota, metabolites, therapy Citation Zhu J, Fu Y, Olovo CV, Xu J, Wu Q, Wei W, Jiang K and Zheng X (2025) The influence of gut microbiota on the gut-brain-kidney axis and its implications for chronic kidney disease

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As more PEGylated therapeutic agents receive FDA approval, more attention has been given to site-specific PEGylation of discrete or monodispersed PEG chains