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Traditional diets that emphasize meat, fish, dairy and eggs are higher in lysine than arginine, while the standard American diet not only tends to be deficient in lysine but oversupplies arginine

Therefore, preventing the oxidation of dopamine to adrenochrome may represent a key neuroprotective strategy for safeguarding the aforementioned neurons that are lost in the substantia nigra in PD (Huenchuguala & Segura-Aguilar, 2024b)

Bawiec CR, Rosnitskiy PB, Peek AT, Maxwell AD, Kreider W, Haar GRT, Sapozhnikov OA, Khokhlova VA, Khokhlova TD

B vitamins decreased the number of M1 macrophages expressing the Ca1.2 channel and increased the number of M2 macrophages expressing the same channel, suggesting a role in M1/M2 transition post-PNI

Assay: Glutathione in mice cells