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All protocols were performed according to the Australian National Health and Medical Research Council Guide for the Care and Use of Laboratory Animals

albicans was rewired by albumin, we overlaid the changes of the intracellular metabolites with the KEGG metabolic pathways map 01100 (Fig

Weighted gene co-expression network analysis (WGCNA) was performed on the selected genes using the WGCNA R package 39

Chang YP, Huang CC, Shen CC, Tsai KC, Ueng YF (2015) Differential inhibition of CYP1-catalyzed regioselective hydroxylation of estradiol by berberine and its oxidative metabolites

Lifestyle and biological factors influence the relationship between mental health and low-grade inflammation

The protection against MPP-induced neurotoxicity was associated with activation of Nrf2 pathway (a crucial defense mechanism against oxidative stress), via the ERK1/2 signaling pathway [57], inhibition of the mitochondrial ROS-dependent oxidative stress, and enhancement of the Erk1/2/Drp1 and Fak/Akt/GSK3 signaling pathways [104]