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As for women, a randomized, doubleblind, placebocontrolled clinical trial involving 150 women (aged 18-39) with clomiphene-resistant PCOS found that adding NAC (1.2 grams/day for five days starting on day three of the cycle) to clomiphene citrate significantly increased both ovulation and pregnancy rates

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Hsa-miR-34a-5p reverses multidrug resistance in gastric cancer cells by targeting the 3-UTR of SIRT1 and inhibiting its expression

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3C), in line with the observed greater abundance of glutathione hydrolase (GGT) in cancer tissue (Fig