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Oral treatment generally requires four to six weeks before noticeable improvements occur , and compliance is essential for success

In a case study involving a young woman treated with high doses of cyanocobalamin for pernicious anemia, acne was one of the first symptoms to appear after a total dose of 12 mg of vitamin B12

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B-12 injection visits are typically efficient

Poor diet, stress, chronic illness, and aging can all contribute to a lack of essential nutrients