nac and l glutathione N-Acetyl Cysteine (NAC)

For instance, in one study, 30 mM GSH strongly inhibited S

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By chelating harmful metals and reducing their bioavailability and toxicity, NAC decreases the production of free radicals, further contributing to its antioxidant and analgesic properties, and potentially improving postoperative outcomes for patients requiring prosthetics with metals linked to systemic toxicity such cobalt and chromium [26]

Similarly, mutations in PINK1 and Parkin have been linked to mitochondrial dysfunction, suggesting that defects in energy metabolism may play a role in the development of PD