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In GCF concentrations of glutathione (range 0.5-2.5 mM) were reported to be 1000 times greater than that normally detected within extracellular tissue compartments (0.5-5 M in human plasma).[29] The high levels of glutathione within GCF may be the result of increased synthesis by cells of the periodontal tissues, or of active release mechanisms or passive release secondary to protease activity on gingival epithelial cells.[4] Neutrophils and/or junctional/crevicular epithelium (JE) are significant contributors for the high concentrations of glutathione in GCF

In plants, under sulfur-limiting conditions they optimize nitrogen assimilation to maintain metabolic homeostasis

Targeted delivery of macrophage membrane biomimetic liposomes through intranasal administration for treatment of ischemic stroke

A comparative study of wild-type (WT) and SR-knockout (SR-KO) mice revealed that the SR is involved primarily in D-serine production in the forebrain of mice, and that there might be other D-serine production pathways may be involved in the brain and peripheral organs (Horio et al., 2011)