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It targets inflammation at its source rather than broadly suppressing the immune system

In in vitro hypoxic conditions, -KG can induce the degradation of HIF-1 in Lewis lung carcinoma, which can inhibit angiogenesis in mouse tumor models and exert an antitumor effect [32]

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In children 6 through 17 years of age, the most common systemic adverse reactions were fatigue, muscle aches, headache, arthralgia, and gastrointestinal symptoms
