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Strober W, Asano N, Fuss I et al (2014) Cellular and molecular mechanisms underlying NOD2 risk-associated polymorphisms in Crohns disease

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24 In addition, a number of powerful preformed inflammatory mediators are released, including cytokines (IL-4, IL-5, IL-6, IL-13, TNF- ) and chemokines (eg CXCL1 and CCL2), histamine, serglycin proteoglycans, and several mast cells-specific proteases (chymases, tryptases, and carboxypeptidase A

Always consult your GP or a qualified healthcare professional to determine the cause of any deficiency and the most appropriate, effective, and safe treatment plan for you