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T helper cells contribute to scar formation through the secretion of IL-4 and IL-13, while regulatory T cells exert an anti-inflammatory effect by producing IL-10 and prostaglandin E2, which inhibit fibrosis (Xu et al., 2024)

These findings suggest that under iron overload, astrocyte-mediated ferritin secretion may mitigate oxidative stress and ferroptosis in dopaminergic neurons, a key process implicated in PD pathogenesis (Zhang et al., 2022b)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 11.James MK, Ray A, Leznova D, Blain SW, Differential modification of p27Kip1 controls its cyclin D-cdk4 inhibitory activity

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