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E., Gerber, C

10.3390/jpm12020128 [DOI] [PMC free article] [PubMed] [Google Scholar] 99

For example, NMR-titration experiments of non-glutathionylated poplar GrxC4 or ScGrx8 with GSH required high glutathione concentrations to detect chemical shifts 47,48 (and titrations of active site serine mutants with GSSG cannot discriminate between both glutathionyl moieties)

hMLH1, hMSH2, and hMSH6 mutations are particularly important in families of patients with Lynch syndrome (Table 3)

The therapeutic efficacy of Ebselen has been studied in experimental diabetic models (de Haan and Cooper 2011)

Ferroptosis is strikingly driven by worsening redox imbalance, which generates and maintains high levels of hydroperoxy-phospholipids (7, 24)
