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[DOI] [PMC free article] [PubMed] [Google Scholar] 51.Gopinath VS, Rao M, Shivahare R, Vishwakarma P, Ghose S, Pradhan A, Hindupur R, Sarma KD, Gupta S, Puri SK, Launay D, Martin D

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Therefore, HPLC gel filtration is recommended as a final polishing step that will isolate properly folded protein from aggregates or other contaminating species

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However, growing evidence indicates that alternative metabolic routes such as malic enzyme 1 (ME1), isocitrate dehydrogenases (IDH1 and IDH2), and the folate cycle also significantly contribute to NADPH production, particularly under stress conditions or during metabolic reprogramming [43]