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In lean C57BL/6J mice, chronic treatment with hGH led to a significant increase in body weight, becoming apparent by day 8
Sigmoidal dose-response curves and reliable estimates of IC 50 values based on non-linear least-squares fitting to the available data could not be obtained since no significant inhibition of DNMT1 and PRMT3 was observed at the tested NNMT inhibitor concentrations (Table 3)
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T2DM The bodys inefficient use of insulin causes T2D
