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doi: 10.1172/JCI169922 71 KirklandJTchkoniaT

In a randomized double-blind placebo controlled parallel group comparison trial, the continuous intake of lutein (12 mg) for 16 weeks as a formulation, considering its bio-accessibility, increased macular pigment optical density (MPOD), improved contrast sensitivity, and prevented decreases in visual function caused by a glare from light (Table 1) [80, 81, 8386]

Plant Physiol Biochem 144:466479

Ethics approval and consent to participate Approved by Ethics Committee, School of Medicine, University of Zagreb, 04-1121-2006 for experiments with rats

Neuropharmacology 63, 974982

Sutton, G